Assay Detail
Functional
CHEMBL3789441
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Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 120 hrs by ATPlite assay
4
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent Progress in Histone Demethylase Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.00 | 6.00 |
| EC50 | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3787669 | — | — | 1 | 6.00 |
| CHEMBL3787547 | — | — | 1 | - |
| CHEMBL3787193 | — | — | 1 | - |
| CHEMBL3786593 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3787669 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL3787547 | — | EC50 | < | 250.0 | nM | - |
| CHEMBL3787193 | — | IC50 | < | 1000.0 | nM | - |
| CHEMBL3786593 | — | IC50 | < | 1000.0 | nM | - |