Assay Detail
Binding
CHEMBL3789701
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of N-terminal flag-tagged recombinant human full length PI4K3alpha expressed in baculovirus infected Sf21 insect cells preincubated for 15 mins followed by addition of cold ATP/gamma32P-ATP measured after 25 mins
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Design and Structural Characterization of Potent and Selective Inhibitors of Phosphatidylinositol 4 Kinase IIIβ.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.55 | 5.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3785311 | — | — | 1 | 5.58 |
| CHEMBL3786230 | — | — | 1 | 5.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3785311 | — | IC50 | = | 2600.0 | nM | 5.58 |
| CHEMBL3786230 | — | IC50 | = | 3000.0 | nM | 5.52 |