Assay Detail
Binding
CHEMBL3790456
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Inhibition of dopamine D2 receptor (unknown origin)
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Classification of matching molecular series on the basis of SAR phenotypes and structural relationships
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 12 | 8.42 | 10.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1257382 | — | — | 1 | 10.24 |
| CHEMBL1257493 | — | — | 1 | 9.24 |
| CHEMBL1257735 | — | — | 1 | 9.24 |
| CHEMBL1257614 | — | — | 1 | 8.81 |
| CHEMBL1257492 | — | — | 1 | 8.68 |
| CHEMBL1258313 | — | — | 1 | 8.24 |
| CHEMBL1258647 | — | — | 1 | 8.13 |
| CHEMBL1257968 | — | — | 1 | 7.94 |
| CHEMBL1258427 | — | — | 1 | 7.80 |
| CHEMBL1258084 | — | — | 1 | 7.65 |
| CHEMBL1257857 | — | — | 1 | 7.65 |
| CHEMBL1258199 | — | — | 1 | 7.45 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1257382 | — | Ki | = | 0.05754 | nM | 10.24 |
| CHEMBL1257493 | — | Ki | = | 0.5754 | nM | 9.24 |
| CHEMBL1257735 | — | Ki | = | 0.5754 | nM | 9.24 |
| CHEMBL1257614 | — | Ki | = | 1.549 | nM | 8.81 |
| CHEMBL1257492 | — | Ki | = | 2.089 | nM | 8.68 |
| CHEMBL1258313 | — | Ki | = | 5.754 | nM | 8.24 |
| CHEMBL1258647 | — | Ki | = | 7.413 | nM | 8.13 |
| CHEMBL1257968 | — | Ki | = | 11.48 | nM | 7.94 |
| CHEMBL1258427 | — | Ki | = | 15.85 | nM | 7.80 |
| CHEMBL1258084 | — | Ki | = | 22.39 | nM | 7.65 |
| CHEMBL1257857 | — | Ki | = | 22.39 | nM | 7.65 |
| CHEMBL1258199 | — | Ki | = | 35.48 | nM | 7.45 |