Assay Detail
Binding
CHEMBL3790873
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Binding affinity to BRPF1B (unknown origin) by isothermal titration calorimetric analysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Disrupting Acetyl-Lysine Recognition: Progress in the Development of Bromodomain Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 7.47 | 7.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3356143 | — | — | 1 | 7.89 |
| CHEMBL3752151 | — | — | 1 | 7.51 |
| CHEMBL3770173 | — | — | 1 | 7.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3356143 | — | Kd | = | 13.0 | nM | 7.89 |
| CHEMBL3752151 | — | Kd | = | 31.0 | nM | 7.51 |
| CHEMBL3770173 | — | Kd | = | 100.0 | nM | 7.00 |