Assay Detail
Binding
CHEMBL3795210
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Uncompetitive inhibition of baker's yeast alpha-glucosidase using pNPG as substrate by Cornish-Bowden plot analysis
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Saccharomyces cerevisiae |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Cinnamic acid amides from Tribulus terrestris displaying uncompetitive α-glucosidase inhibition.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 12 | 5.53 | 6.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL325749 | — | — | 1 | 6.54 |
| CHEMBL64286 | N-P-COUMAROYL TYRAMINE | — | 1 | 6.46 |
| CHEMBL3792801 | — | — | 1 | 5.86 |
| CHEMBL2296788 | — | — | 1 | 5.76 |
| CHEMBL206646 | — | — | 1 | 5.75 |
| CHEMBL206555 | N-TRANS-FERULOYL TYRAMINE | — | 1 | 4.95 |
| CHEMBL18026 | — | — | 1 | 4.74 |
| CHEMBL3792932 | — | — | 1 | 4.21 |
| CHEMBL3793646 | — | — | 1 | - |
| CHEMBL3792825 | — | — | 1 | - |
| CHEMBL417389 | — | — | 1 | - |
| CHEMBL307429 | DUVOGLUSTAT | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL325749 | — | Ki | = | 290.0 | nM | 6.54 |
| CHEMBL64286 | N-P-COUMAROYL TYRAMINE | Ki | = | 350.0 | nM | 6.46 |
| CHEMBL3792801 | — | Ki | = | 1380.0 | nM | 5.86 |
| CHEMBL2296788 | — | Ki | = | 1740.0 | nM | 5.76 |
| CHEMBL206646 | — | Ki | = | 1770.0 | nM | 5.75 |
| CHEMBL206555 | N-TRANS-FERULOYL TYRAMINE | Ki | = | 11320.0 | nM | 4.95 |
| CHEMBL18026 | — | Ki | = | 18210.0 | nM | 4.74 |
| CHEMBL3792932 | — | Ki | = | 62100.0 | nM | 4.21 |
| CHEMBL3793646 | — | Ki | - | — | - | |
| CHEMBL3792825 | — | Ki | - | — | - | |
| CHEMBL417389 | — | Ki | - | — | - | |
| CHEMBL307429 | DUVOGLUSTAT | Ki | - | — | - |