Assay Detail
Functional
CHEMBL3795778
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Antiplasmodial activity against Plasmodium falciparum Dd2 incubated under low oxygen conditions after 72 hrs by SYBR green assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antiplasmodial phloroglucinol derivatives from Syncarpia glomulifera.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 6.20 | 8.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL269671 | ARTEMISININ | 3.0 | 1 | 8.21 |
| CHEMBL3793563 | — | — | 1 | 7.00 |
| CHEMBL269277 | BETULINIC ACID | 1.0 | 1 | 5.46 |
| CHEMBL3793864 | — | — | 1 | 5.42 |
| CHEMBL410525 | O-ACETYLURSOLIC ACID | — | 1 | 4.92 |
| CHEMBL281335 | — | — | 1 | - |
| CHEMBL169 | URSOLIC ACID | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL269671 | ARTEMISININ | IC50 | = | 6.2 | nM | 8.21 |
| CHEMBL3793563 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL269277 | BETULINIC ACID | IC50 | = | 3440.0 | nM | 5.46 |
| CHEMBL3793864 | — | IC50 | = | 3810.0 | nM | 5.42 |
| CHEMBL410525 | O-ACETYLURSOLIC ACID | IC50 | = | 12090.0 | nM | 4.92 |
| CHEMBL281335 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL169 | URSOLIC ACID | IC50 | > | 40000.0 | nM | - |