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Assay Detail

CHEMBL3796290

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Binding
Inhibition of rat liver CK2 preincubated for 5 mins followed by substrate addition measured after 40 mins by radiometric kinase assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Design and synthesis of novel protein kinase CK2 inhibitors on the base of 4-aminothieno[2,3-d]pyrimidines.
Ostrynska OV, Balanda AO, Bdzhola VG, Golub AG, Kotey IM, Kukharenko OP, Gryshchenko AA, Briukhovetska NV, Yarmoluk SM.
Eur J Med Chem (2016) 115 : 148 -160
PubMed 27017545 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.77 6.77

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL92361 1 6.77

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL92361 Ki = 170.0 nM 6.77