Assay Detail
Binding
CHEMBL3801018
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Binding affinity to human recombinant CA13 after 30 secs by surface plasmon resonance assay
13
Total Activities
13
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Kinetically Selective Inhibitors of Human Carbonic Anhydrase Isozymes I, II, VII, IX, XII, and XIII.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 13 | 7.32 | 8.49 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3798446 | — | — | 1 | 8.49 |
| CHEMBL2010994 | — | — | 1 | 8.38 |
| CHEMBL2443188 | — | — | 1 | 8.19 |
| CHEMBL3797893 | — | — | 1 | 7.96 |
| CHEMBL3798303 | — | — | 1 | 7.82 |
| CHEMBL3797385 | — | — | 1 | 7.62 |
| CHEMBL2011156 | — | — | 1 | 7.21 |
| CHEMBL2011155 | — | — | 1 | 6.75 |
| CHEMBL3799945 | — | — | 1 | 6.68 |
| CHEMBL1272242 | — | — | 1 | 6.29 |
| CHEMBL3799296 | — | — | 1 | 6.28 |
| CHEMBL2443189 | — | — | 1 | 6.15 |
| CHEMBL1272187 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3798446 | — | Kd | = | 3.2 | nM | 8.49 |
| CHEMBL2010994 | — | Kd | = | 4.2 | nM | 8.38 |
| CHEMBL2443188 | — | Kd | = | 6.4 | nM | 8.19 |
| CHEMBL3797893 | — | Kd | = | 11.0 | nM | 7.96 |
| CHEMBL3798303 | — | Kd | = | 15.0 | nM | 7.82 |
| CHEMBL3797385 | — | Kd | = | 24.0 | nM | 7.62 |
| CHEMBL2011156 | — | Kd | = | 61.0 | nM | 7.21 |
| CHEMBL2011155 | — | Kd | = | 180.0 | nM | 6.75 |
| CHEMBL3799945 | — | Kd | = | 210.0 | nM | 6.68 |
| CHEMBL1272242 | — | Kd | = | 510.0 | nM | 6.29 |
| CHEMBL3799296 | — | Kd | = | 520.0 | nM | 6.28 |
| CHEMBL2443189 | — | Kd | = | 710.0 | nM | 6.15 |
| CHEMBL1272187 | — | Kd | - | — | - |