Assay Detail
Functional
CHEMBL3801302
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Antiinflammatory activity against mouse J774 cells assessed as inhibition of LPS-induced iNOS expression after 24 hrs by Western blot analysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | J774 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Betulin Derivatives Effectively Suppress Inflammation in Vitro and in Vivo.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.52 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1087753 | — | — | 1 | 6.52 |
| CHEMBL221890 | — | — | 1 | 6.52 |
| CHEMBL3134503 | — | — | 1 | 6.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1087753 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL221890 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL3134503 | — | IC50 | = | 300.0 | nM | 6.52 |