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Assay Detail

CHEMBL3801386

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against mCMV infected in mouse NIH 3T3 cells treated for 10 mins measured after 24 hrs
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Maize chlorotic mottle virus
Cell Type NIH3T3
Confidence 1 — Organism
Curated By Autocuration

Target

Maize chlorotic mottle virus (CHEMBL612939)
Type ORGANISM
Organism Maize chlorotic mottle virus

Publication

Rigid amphipathic nucleosides suppress reproduction of the tick-borne encephalitis virus
Orlov AA, Chistov AA, Kozlovskaya LI, Ustinov AV, Korshun VA, Karganova GG, Osolodkin DI
Medchemcomm (2016) 7 : 495 -499
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 8.70 8.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3797928 1 8.70
CHEMBL3798024 1 8.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3797928 IC50 = 2.0 nM 8.70
CHEMBL3798024 IC50 = 2.0 nM 8.70