Assay Detail
Binding
CHEMBL3802802
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to Burkholderia cenocepacia J2315 BC2L-A expressed in Escherichia coli BL21 (DE3) cells by microcalorimetry
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Burkholderia cenocepacia J2315 |
| Cell Type | BL21-DE3 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Lectin (CHEMBL3797020) ↗| Type | SINGLE PROTEIN |
| Organism | Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656/ NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)) |
Publication
Development of a competitive binding assay for the Burkholderia cenocepacia lectin BC2L-A and structure activity relationship of natural and synthetic inhibitors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 5.43 | 5.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL195368 | — | — | 1 | 5.57 |
| CHEMBL469448 | D-MANNOSE | 2.0 | 1 | 5.29 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL195368 | — | Kd | = | 2700.0 | nM | 5.57 |
| CHEMBL469448 | D-MANNOSE | Kd | = | 5150.0 | nM | 5.29 |