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Assay Detail

CHEMBL3802946

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Antagonist activity at P2Y12 receptor (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

P2Y purinoceptor 12 (CHEMBL2001)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

State of affairs: Design and structure-activity relationships of reversible P2Y12 receptor antagonists.
Zetterberg F, Svensson P.
Bioorg Med Chem Lett (2016) 26 : 2739 -2754
PubMed 27133596 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.30 8.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL398435 TICAGRELOR 4.0 1 8.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL398435 TICAGRELOR IC50 = 5.012 nM 8.30