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Assay Detail

CHEMBL3804643

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Covalent inhibition of MIF (unknown origin) tautomerase activity using 4-hydroxyphenyl pyruvic acid as substrate
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Macrophage migration inhibitory factor (CHEMBL2085)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Irregularities in enzyme assays: The case of macrophage migration inhibitory factor.
Cisneros JA, Robertson MJ, Valhondo M, Jorgensen WL.
Bioorg Med Chem Lett (2016) 26 : 2764 -2767
PubMed 27156768 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.44 6.44

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3797437 1 6.44

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3797437 IC50 = 360.0 nM 6.44