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Assay Detail

CHEMBL3806573

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Physicochemical
Metal chelating activity of the compound assessed as ferrous ion complex formation after 10 mins
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Physicochemical
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Publication

Novel 1,3-thiazolidin-4-one derivatives as promising anti-Candida agents endowed with anti-oxidant and chelating properties.
Secci D, Carradori S, Bizzarri B, Chimenti P, De Monte C, Mollica A, Rivanera D, Zicari A, Mari E, Zengin G, Aktumsek A.
Eur J Med Chem (2016) 117 : 144 -156
PubMed 27100030 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 12 4.70 4.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL858 EDETIC ACID 3.0 1 4.70
CHEMBL3804917 1 -
CHEMBL3804938 1 -
CHEMBL3804833 1 -
CHEMBL3805097 1 -
CHEMBL3805651 1 -
CHEMBL3805135 1 -
CHEMBL3805677 1 -
CHEMBL3805406 1 -
CHEMBL3805073 1 -
CHEMBL3805577 1 -
CHEMBL3805620 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL858 EDETIC ACID IC50 = 20000.0 nM 4.70
CHEMBL3804917 IC50 > 5000000.0 nM -
CHEMBL3804938 IC50 > 5000000.0 nM -
CHEMBL3804833 IC50 > 5000000.0 nM -
CHEMBL3805097 IC50 = 3840000.0 nM -
CHEMBL3805651 IC50 = 4640000.0 nM -
CHEMBL3805135 IC50 = 3900000.0 nM -
CHEMBL3805677 IC50 = 3670000.0 nM -
CHEMBL3805406 IC50 = 1640000.0 nM -
CHEMBL3805073 IC50 = 2760000.0 nM -
CHEMBL3805577 IC50 > 5000000.0 nM -
CHEMBL3805620 IC50 > 5000000.0 nM -