Assay Detail
Functional
CHEMBL3812646
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Antiviral activity against HCV genotype 3a NC009824 assessed as decrease in HCV replicon RNA replication by taqman assay based cell based replicon method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Hepacivirus hominis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of fused tricyclic core containing HCV NS5A inhibitors with pan-genotype activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 10.70 | 10.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3039514 | ELBASVIR | 4.0 | 1 | 10.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3039514 | ELBASVIR | EC50 | = | 0.02 | nM | 10.70 |