Assay Detail
Binding
CHEMBL3812673
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Competitive inhibition of Bacillus cereus 569/H/9 metallo-beta-lactamase Bc2 expressed in Escherichia coli GI724 cells using nitrocefin as substrate by spectrometry method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bacillus cereus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Triazolylthioacetamide: A Valid Scaffold for the Development of New Delhi Metallo-β-Lactmase-1 (NDM-1) Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.47 | 7.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3809419 | — | — | 1 | 7.05 |
| CHEMBL3808751 | — | — | 1 | 5.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3809419 | — | Ki | = | 90.0 | nM | 7.05 |
| CHEMBL3808751 | — | Ki | = | 1280.0 | nM | 5.89 |