Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL3812915

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [3H]CP 55940 from human CB1 receptor after 1 hr by liquid scintillation spectrometry
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cannabinoid receptor 1 (CHEMBL218)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Discovery of KLS-13019, a Cannabidiol-Derived Neuroprotective Agent, with Improved Potency, Safety, and Permeability.
Kinney WA, McDonnell ME, Zhong HM, Liu C, Yang L, Ling W, Qian T, Chen Y, Cai Z, Petkanas D, Brenneman DE.
ACS Med Chem Lett (2016) 7 : 424 -428
PubMed 27096053 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 7.72 7.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3809355 1 7.96
CHEMBL125061 1 7.48

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3809355 Ki = 11.0 nM 7.96
CHEMBL125061 Ki = 33.0 nM 7.48