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Assay Detail

CHEMBL3812936

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Binding
Binding affinity to Escherichia coli DNA gyrase B
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Escherichia coli
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

New N-phenyl-4,5-dibromopyrrolamides and N-Phenylindolamides as ATPase inhibitors of DNA gyrase.
Zidar N, Tomašič T, Macut H, Sirc A, Brvar M, Montalvão S, Tammela P, Ilaš J, Kikelj D.
Eur J Med Chem (2016) 117 : 197 -211
PubMed 27100032 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 7.72 7.72

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL36506 NOVOBIOCIN 4.0 1 7.72

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL36506 NOVOBIOCIN Kd = 19.0 nM 7.72