Assay Detail
Binding
CHEMBL3815765
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human PDK1
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
3-phosphoinositide-dependent protein kinase 1 (CHEMBL2534) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Discovery of novel 7-azaindoles as PDK1 inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.25 | 5.27 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL50498 | MERIDIANIN A | — | 1 | 5.27 |
| CHEMBL405665 | MERIOLIN 1 | — | 1 | 5.23 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL50498 | MERIDIANIN A | IC50 | = | 5400.0 | nM | 5.27 |
| CHEMBL405665 | MERIOLIN 1 | IC50 | = | 5900.0 | nM | 5.23 |