Assay Detail
ADMET
CHEMBL3815917
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Cytotoxicity against human HT-29 cells after 72 hrs by SRB assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | HT-29 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antileishmanial and Cytotoxic Activity of Some Highly Oxidized Abietane Diterpenoids from the Bald Cypress, Taxodium distichum.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.94 | 5.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL235195 | TAXODIONE | — | 1 | 5.60 |
| CHEMBL3814907 | — | — | 1 | 5.36 |
| CHEMBL488040 | 14-DEOXYCOLEON U | — | 1 | 4.88 |
| CHEMBL3814903 | — | — | 1 | 4.44 |
| CHEMBL197308 | FERRUGINOL | — | 1 | 4.41 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL235195 | TAXODIONE | IC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL3814907 | — | IC50 | = | 4400.0 | nM | 5.36 |
| CHEMBL488040 | 14-DEOXYCOLEON U | IC50 | = | 13300.0 | nM | 4.88 |
| CHEMBL3814903 | — | IC50 | = | 36000.0 | nM | 4.44 |
| CHEMBL197308 | FERRUGINOL | IC50 | = | 39400.0 | nM | 4.41 |