Assay Detail
Binding
CHEMBL3816588
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of BACE1 (unknown origin) using peptide substrate by time-course measurement-based fluorescence analysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Tasiamide F, a potent inhibitor of cathepsins D and E from a marine cyanobacterium.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.69 | 7.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2181015 | — | — | 1 | 7.10 |
| CHEMBL378225 | — | — | 1 | 6.80 |
| CHEMBL3813928 | — | — | 1 | 6.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2181015 | — | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL378225 | — | IC50 | = | 160.0 | nM | 6.80 |
| CHEMBL3813928 | — | IC50 | = | 690.0 | nM | 6.16 |