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Assay Detail

CHEMBL3816779

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human FLT3 using EAIYAAPFAKKK as substrate after 40 mins by scintillation counting method in presence of [gamma-33P-ATP]
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Receptor-type tyrosine-protein kinase FLT3 (CHEMBL1974)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

De Novo Design at the Edge of Chaos.
Schneider P, Schneider G.
J Med Chem (2016) 59 : 4077 -4086
PubMed 26881908 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.15 8.15

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2046699 1 8.15

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2046699 IC50 = 7.0 nM 8.15