Assay Detail
Binding
CHEMBL3817029
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Agonist activity at human LXRbeta coexpressed in African green monkey CV1 cells by Gal4 responsive reporter gene assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CV-1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of a Novel, Orally Efficacious Liver X Receptor (LXR) β Agonist.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 7.15 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3814006 | — | — | 1 | 7.52 |
| CHEMBL434302 | 24(S),25-EPOXYCHOLESTEROL | — | 1 | 6.78 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3814006 | — | EC50 | = | 30.0 | nM | 7.52 |
| CHEMBL434302 | 24(S),25-EPOXYCHOLESTEROL | EC50 | = | 168.0 | nM | 6.78 |