Assay Detail
Binding
CHEMBL3819988
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of bovine brain synapsin-1 incubated for 1 hr by ATP-[gamma35S] binding assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Impact of Binding Site Comparisons on Medicinal Chemistry and Rational Molecular Design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.37 | 6.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL413552 | QUERCETAGETIN | — | 1 | 6.82 |
| CHEMBL3818384 | — | — | 1 | 6.30 |
| CHEMBL14762 | SELICICLIB | 2.0 | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL413552 | QUERCETAGETIN | IC50 | = | 150.0 | nM | 6.82 |
| CHEMBL3818384 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL14762 | SELICICLIB | IC50 | = | 1000.0 | nM | 6.00 |