Assay Detail
Binding
CHEMBL3820004
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of FITC-labeled Bid BH3 peptide binding to GST-tagged MCL1 harboring N-terminal and C-terminal point mutant (unknown origin) expressed in Escherichia coli Bl21(DE3) cells by fluorescence polarization assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Leukemia cell |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Small molecules targeting Mcl-1: the search for a silver bullet in cancer therapy
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.32 | 5.32 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3265288 | — | — | 1 | 5.32 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3265288 | — | IC50 | = | 4780.0 | nM | 5.32 |