Assay Detail
Binding
CHEMBL3821022
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Influenza A virus (A/Aichi/75/2008(H3N2)) neuraminidase N2 activity using 4MU-Neu5Ac as substrate preincubated for 15 mins followed by substrate addition measured after 15 mins by fluorescence analysis
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Influenza A virus (A/Aichi/75/2008(H3N2)) |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
A Novel Potent and Highly Specific Inhibitor against Influenza Viral N1-N9 Neuraminidases: Insight into Neuraminidase-Inhibitor Interactions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.62 | 8.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3818159 | — | — | 1 | 8.16 |
| CHEMBL222813 | ZANAMIVIR | 4.0 | 1 | 7.94 |
| CHEMBL3818654 | — | — | 1 | 7.87 |
| CHEMBL3819510 | — | — | 1 | 6.51 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3818159 | — | IC50 | = | 6.94 | nM | 8.16 |
| CHEMBL222813 | ZANAMIVIR | IC50 | = | 11.51 | nM | 7.94 |
| CHEMBL3818654 | — | IC50 | = | 13.63 | nM | 7.87 |
| CHEMBL3819510 | — | IC50 | = | 311.25 | nM | 6.51 |