Assay Detail
Binding
CHEMBL3821986
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Competitive inhibition of N-terminally fluorescein-labeled human BCL9 (350 to 375 residues) interaction with beta-catenin E155A mutant (138 to 686 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 after 3 hrs by fluorescence polarization assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Structure-Based Design of 1,4-Dibenzoylpiperazines as β-Catenin/B-Cell Lymphoma 9 Protein-Protein Interaction Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 4.41 | 4.41 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3819506 | — | — | 1 | 4.41 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3819506 | — | Ki | = | 39000.0 | nM | 4.41 |