Assay Detail
Binding
CHEMBL3829323
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of NS5A in HCV genotype 2b
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Hepatitis C virus subtype 2b |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Alkyl substituted aminal derivatives of HCV NS5A inhibitor MK-8742.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 8.02 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3039514 | ELBASVIR | 4.0 | 1 | 8.52 |
| CHEMBL3828072 | — | — | 1 | 7.51 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3039514 | ELBASVIR | EC50 | = | 3.0 | nM | 8.52 |
| CHEMBL3828072 | — | EC50 | = | 31.0 | nM | 7.51 |