Assay Detail
Binding
CHEMBL3829807
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Inhibition of bovine factor 10a using Boc-Ile-Glu-Gly-Arg-AMC as substrate after 20 mins by fluorimetric analysis
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Evaluation of bisbenzamidines as inhibitors for matriptase-2.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 5.39 | 6.49 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL365916 | — | — | 1 | 6.49 |
| CHEMBL3594082 | — | — | 1 | 6.41 |
| CHEMBL3594083 | — | — | 1 | 5.89 |
| CHEMBL269032 | — | — | 1 | 5.11 |
| CHEMBL181480 | — | — | 1 | 4.86 |
| CHEMBL9126 | — | — | 1 | 4.70 |
| CHEMBL3828410 | — | — | 1 | 4.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL365916 | — | Ki | = | 327.0 | nM | 6.49 |
| CHEMBL3594082 | — | Ki | = | 391.0 | nM | 6.41 |
| CHEMBL3594083 | — | Ki | = | 1290.0 | nM | 5.89 |
| CHEMBL269032 | — | Ki | = | 7830.0 | nM | 5.11 |
| CHEMBL181480 | — | Ki | = | 13700.0 | nM | 4.86 |
| CHEMBL9126 | — | Ki | = | 20000.0 | nM | 4.70 |
| CHEMBL3828410 | — | Ki | = | 52300.0 | nM | 4.28 |