Assay Detail
Binding
CHEMBL3829991
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Activation of PPARbeta-LBD (unknown origin) assessed as fluorescein-labeled coactivator C33 recruitment by TR-FRET assay
3
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Peroxisome proliferator-activated receptor delta (CHEMBL3979) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Syringaresinol induces mitochondrial biogenesis through activation of PPARβ pathway in skeletal muscle cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.96 | 7.17 |
| Activity | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL38508 | — | — | 1 | 7.17 |
| CHEMBL361362 | SYRINGARESINOL | — | 2 | 4.74 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL38508 | — | EC50 | = | 67.11 | nM | 7.17 |
| CHEMBL361362 | SYRINGARESINOL | EC50 | = | 18110.0 | nM | 4.74 |
| CHEMBL361362 | SYRINGARESINOL | Activity | - | — | - |