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Assay Detail

CHEMBL3854432

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of TNF-alpha-activated NFkappaB (unknown origin) transfected in HEK293 cells after 6 hrs by luciferase reporter gene assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type HEK293
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Anti-inflammatory and Quinone Reductase Inducing Compounds from Fermented Noni (Morinda citrifolia) Juice Exudates.
Youn UJ, Park EJ, Kondratyuk TP, Sang-Ngern M, Wall MM, Wei Y, Pezzuto JM, Chang LC.
J Nat Prod (2016) 79 : 1508 -1513
PubMed 27196335 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.42 5.42

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL60718 TPCK 1 5.42

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL60718 TPCK IC50 = 3800.0 nM 5.42