Assay Detail
Binding
CHEMBL3856547
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CDK2 (unknown origin)
3
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Cyclin Dependent Kinase 9 Inhibitors for Cancer Therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.77 | 8.70 |
| IC50 | 1 | 8.52 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL298445 | — | — | 1 | 8.70 |
| CHEMBL1944698 | ZOTIRACICLIB | 2.0 | 1 | 8.52 |
| CHEMBL3932121 | — | — | 1 | 6.83 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL298445 | — | Ki | = | 2.0 | nM | 8.70 |
| CHEMBL1944698 | ZOTIRACICLIB | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL3932121 | — | Ki | = | 149.0 | nM | 6.83 |