Assay Detail
Binding
CHEMBL3857905
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of dopamine transporter (unknown origin) assessed as suppression of synaptosomal uptake of dopamine
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Sodium-dependent dopamine transporter (CHEMBL238) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Polycyclic Polyprenylated Acylphloroglucinol Congeners from Hypericum scabrum.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.70 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1237210 | — | — | 1 | 5.70 |
| CHEMBL536352 | — | — | 1 | 5.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1237210 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL536352 | — | IC50 | = | 2000.0 | nM | 5.70 |