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Assay Detail

CHEMBL3860138

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antioxidant activity assessed as AAPH free radical scavenging activity measured every min during 240 mins by fluorescein-based oxygen radical absorption capacity assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Publication

Do cinnamylideneacetophenones have antioxidant properties and a protective effect toward the oxidation of phosphatidylcholines?
Silva EMP, Melo T, Sousa BC, Resende DISP, Magalhães LM, Segundo MA, Silva AMS, Domingues MRM.
Eur J Med Chem (2016) 121 : 331 -337
PubMed 27267003 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 5.63 5.92

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3919650 1 5.92
CHEMBL140 CURCUMIN 3.0 1 5.75
CHEMBL3941602 1 5.48
CHEMBL153 TROLOX 1 5.38

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3919650 IC50 = 1200.0 nM 5.92
CHEMBL140 CURCUMIN IC50 = 1800.0 nM 5.75
CHEMBL3941602 IC50 = 3300.0 nM 5.48
CHEMBL153 TROLOX IC50 = 4200.0 nM 5.38