Assay Detail
Binding
CHEMBL3861263
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of PI3Kalpha/p85alpha (unknown origin) using phosphatidylinositol and gamma-32P-ATP incubated for 20 mins by TLC assay or high-throughput membrane capture assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Class II Phosphoinositide 3-Kinases as Novel Drug Targets.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.90 | 8.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3913354 | — | — | 1 | 8.10 |
| CHEMBL1241857 | — | — | 1 | 7.96 |
| CHEMBL3922359 | — | — | 1 | 7.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3913354 | — | IC50 | = | 8.0 | nM | 8.10 |
| CHEMBL1241857 | — | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL3922359 | — | IC50 | = | 23.0 | nM | 7.64 |