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Assay Detail

CHEMBL3862621

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Agonist activity at mouse YFP-tagged TRPV3 expressed in HEK293 cells assessed as increase in calcium influx by Fluo-2-AM dye based microscopic analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Mus musculus
Cell Type HEK293
Confidence 9 — Direct single protein target
Curated By Autocuration

Publication

Neuroactive and Anti-inflammatory Frankincense Cembranes: A Structure-Activity Study.
Pollastro F, Golin S, Chianese G, Putra MY, Schiano Moriello A, De Petrocellis L, García V, Munoz E, Taglialatela-Scafati O, Appendino G.
J Nat Prod (2016) 79 : 1762 -1768
PubMed 27352042 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 4.80 4.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3979367 1 4.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3979367 EC50 = 16000.0 nM 4.80