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Assay Detail

CHEMBL3862732

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to human PIK3CG expressed in Escherichia coli BL21 cells incubated for 1 hr by active site directed binding competition assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type BL21
Confidence 9 — Direct single protein target
Curated By Autocuration

Publication

Discovery of a Selective Aurora A Kinase Inhibitor by Virtual Screening.
Kilchmann F, Marcaida MJ, Kotak S, Schick T, Boss SD, Awale M, Gönczy P, Reymond JL.
J Med Chem (2016) 59 : 7188 -7211
PubMed 27391133 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 5.82 5.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3921246 1 5.82

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3921246 Kd = 1500.0 nM 5.82