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Assay Detail

CHEMBL3863294

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Binding
Binding affinity to histamine H4 receptor (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Histamine H4 receptor (CHEMBL3759)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Synthesis and evaluation of a 2-benzothiazolylphenylmethyl ether class of histamine H4 receptor antagonists.
Labeeuw O, Levoin N, Billot X, Danvy D, Calmels T, Krief S, Ligneau X, Berrebi-Bertrand I, Robert P, Lecomte JM, Schwartz JC, Capet M.
Bioorg Med Chem Lett (2016) 26 : 5263 -5266
PubMed 27692832 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 6.88 8.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL90 HISTAMINE 4.0 1 8.80
CHEMBL507 N-METHYLHISTAMINE 1 4.96

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL90 HISTAMINE Ki = 1.6 nM 8.80
CHEMBL507 N-METHYLHISTAMINE Ki = 11000.0 nM 4.96