Assay Detail
Binding
CHEMBL3863415
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant human MAO-A expressed in insect cell microsomes using kynuramine as substrate assessed as decrease in 4-hydroxyquinoline production incubated for 20 mins by fluorescence spectrophotometry
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Neuroprotective effects of benzyloxy substituted small molecule monoamine oxidase B inhibitors in Parkinson's disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.82 | 5.93 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3927065 | — | — | 1 | 5.93 |
| CHEMBL3892863 | — | — | 1 | 5.82 |
| CHEMBL3770875 | — | — | 1 | 5.71 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3927065 | — | IC50 | = | 1170.0 | nM | 5.93 |
| CHEMBL3892863 | — | IC50 | = | 1520.0 | nM | 5.82 |
| CHEMBL3770875 | — | IC50 | = | 1970.0 | nM | 5.71 |