Assay Detail
Binding
CHEMBL3864080
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of 6xHisGB1 tagged PI4KB (unknown origin) expressed in Escherichia coli BL21 Star
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Fluorescent Inhibitors as Tools To Characterize Enzymes: Case Study of the Lipid Kinase Phosphatidylinositol 4-Kinase IIIβ (PI4KB).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.27 | 7.87 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3974986 | — | — | 1 | 7.87 |
| CHEMBL3966476 | — | — | 1 | 7.41 |
| CHEMBL3963020 | — | — | 1 | 7.12 |
| CHEMBL3936684 | — | — | 1 | 6.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3974986 | — | IC50 | = | 13.4 | nM | 7.87 |
| CHEMBL3966476 | — | IC50 | = | 39.4 | nM | 7.41 |
| CHEMBL3963020 | — | IC50 | = | 76.3 | nM | 7.12 |
| CHEMBL3936684 | — | IC50 | = | 208.5 | nM | 6.68 |