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Assay Detail

CHEMBL3866487

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of CDK2 (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cyclin-dependent kinase 2 (CHEMBL301)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

3-Hydrazinoindolin-2-one derivatives: Chemical classification and investigation of their targets as anticancer agents.
Ibrahim HS, Abou-Seri SM, Abdel-Aziz HA.
Eur J Med Chem (2016) 122 : 366 -381
PubMed 27391135 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.22 7.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL411491 1 7.22

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL411491 IC50 = 60.0 nM 7.22