Assay Detail
Binding
CHEMBL3867291
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of HIV1 integrase activity assessed as suppression of viral replication in human H9 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Human immunodeficiency virus 1 |
| Cell Type | H9 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Incorporation of Privileged Structures into Bevirimat Can Improve Activity against Wild-Type and Bevirimat-Resistant HIV-1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.70 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL518243 | LITHOSPERMIC ACID | — | 1 | 5.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL518243 | LITHOSPERMIC ACID | IC50 | = | 2000.0 | nM | 5.70 |