Assay Detail
Functional
CHEMBL3869474
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Induction of apoptosis in human PC3 cells after 72 hrs by crystal violet staining based assay
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PC-3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Novel synthetic chalcones induce apoptosis in the A549 non-small cell lung cancer cells harboring a KRAS mutation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 1 | - | - |
| EC50 | 1 | 6.35 | 6.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3919996 | — | — | 2 | 6.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3919996 | — | EC50 | = | 450.0 | nM | 6.35 |
| CHEMBL3919996 | — | Activity | - | — | - |