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Assay Detail

CHEMBL3871208

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to human MIF by fluorescence polarization assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Macrophage migration inhibitory factor (CHEMBL2085)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Systematic Study of Effects of Structural Modifications on the Aqueous Solubility of Drug-like Molecules.
Cisneros JA, Robertson MJ, Mercado BQ, Jorgensen WL.
ACS Med Chem Lett (2017) 8 : 124 -127
PubMed 28105287 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 4.62 4.62

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3798703 1 4.62

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3798703 Kd = 24000.0 nM 4.62