Assay Detail
Binding
CHEMBL3871960
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Competitive inhibition of Trypanosoma brucei rhodesain in presence of varying levels of Cbz-Phe-Arg-AMC substrate by Cheng-Prusoff equation analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Trypanosoma brucei |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Evaluation of dipeptide nitriles as inhibitors of rhodesain, a major cysteine protease of Trypanosoma brucei.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.44 | 8.59 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3805662 | — | — | 1 | 8.59 |
| CHEMBL1651359 | — | — | 1 | 8.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3805662 | — | Ki | = | 2.6 | nM | 8.59 |
| CHEMBL1651359 | — | Ki | = | 5.3 | nM | 8.28 |