Assay Detail
Toxicity
CHEMBL3873374
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Hepatotoxicity in human HepG2 cells assessed as intracellular ATP level after 48 hrs by luminescence based ATP detection assay
5
Total Activities
5
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Toxicity |
| Organism | Homo sapiens |
| Cell Type | HepG2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design, synthesis, and biological evaluation of fluorinated imidazo[1,2-a]pyridine derivatives with potential antipsychotic activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 4 | - | - |
| IC50 | 1 | 5.14 | 5.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL224214 | CARBONYL CYANIDE M-CHLOROPHENYLHYDRAZONE | — | 1 | 5.14 |
| CHEMBL3971200 | — | — | 1 | - |
| CHEMBL3962969 | — | — | 1 | - |
| CHEMBL3954951 | — | — | 1 | - |
| CHEMBL911 | ZOLPIDEM | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL224214 | CARBONYL CYANIDE M-CHLOROPHENYLHYDRAZONE | IC50 | = | 7200.0 | nM | 5.14 |
| CHEMBL3971200 | — | Activity | - | — | - | |
| CHEMBL3962969 | — | Activity | - | — | - | |
| CHEMBL3954951 | — | Activity | - | — | - | |
| CHEMBL911 | ZOLPIDEM | Activity | - | — | - |