Assay Detail
Binding
CHEMBL3874935
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human His10-tagged CREBBP expressed in Escherichia coli BL21(DE3)-R3 using 1% DMSO by SPR assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of New Bromodomain Scaffolds by Biosensor Fragment Screening.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 4.57 | 5.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3959972 | — | — | 1 | 5.15 |
| CHEMBL1230189 | — | — | 1 | 3.99 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3959972 | — | Kd | = | 7080.0 | nM | 5.15 |
| CHEMBL1230189 | — | Kd | = | 103000.0 | nM | 3.99 |