Assay Detail
Binding
CHEMBL3875269
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of thiazole orange binding to duplex DNA (unknown origin) by fluorescence assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Not specified |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Quinolino[3,4-b]quinoxalines and pyridazino[4,3-c]quinoline derivatives: Synthesis, inhibition of topoisomerase IIα, G-quadruplex binding and cytotoxic properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.43 | 5.90 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3883611 | — | — | 1 | 5.90 |
| CHEMBL3883419 | — | — | 1 | 4.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3883611 | — | EC50 | = | 1260.0 | nM | 5.90 |
| CHEMBL3883419 | — | EC50 | = | 10880.0 | nM | 4.96 |