Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL3875348

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antioxidant activity assessed as inhibition of beta carotene/ linoleic acid peroxidation after 120 mins by spectrophotometric analysis
20
Total Activities
20
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Publication

New piperidine-hydrazone derivatives: Synthesis, biological evaluations and molecular docking studies as AChE and BChE inhibitors.
Karaman N, Sıcak Y, Taşkın-Tok T, Öztürk M, Karaküçük-İyidoğan A, Dikmen M, Koçyiğit-Kaymakçıoğlu B, Oruç-Emre EE.
Eur J Med Chem (2016) 124 : 270 -283
PubMed 27592396 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 20 4.43 5.63

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL146 BUTYLATED HYDROXYTOLUENE 2.0 1 5.63
CHEMBL47 ALPHA-TOCOPHEROL 1 5.35
CHEMBL3884685 1 4.55
CHEMBL3883826 1 4.55
CHEMBL3884920 1 4.46
CHEMBL3884157 1 4.39
CHEMBL3885314 1 4.39
CHEMBL3884571 1 4.38
CHEMBL3884922 1 4.36
CHEMBL3883957 1 4.34
CHEMBL3884514 1 4.31
CHEMBL3884946 1 4.28
CHEMBL3883629 1 4.26
CHEMBL3885249 1 4.25
CHEMBL3885058 1 4.18
CHEMBL3885095 1 4.17
CHEMBL3885375 1 4.16
CHEMBL3885089 1 4.14
CHEMBL3884675 1 4.11
CHEMBL3883584 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL146 BUTYLATED HYDROXYTOLUENE IC50 = 2340.0 nM 5.63
CHEMBL47 ALPHA-TOCOPHEROL IC50 = 4500.0 nM 5.35
CHEMBL3884685 IC50 = 27830.0 nM 4.55
CHEMBL3883826 IC50 = 28150.0 nM 4.55
CHEMBL3884920 IC50 = 34460.0 nM 4.46
CHEMBL3884157 IC50 = 41080.0 nM 4.39
CHEMBL3885314 IC50 = 40240.0 nM 4.39
CHEMBL3884571 IC50 = 41850.0 nM 4.38
CHEMBL3884922 IC50 = 43560.0 nM 4.36
CHEMBL3883957 IC50 = 45160.0 nM 4.34
CHEMBL3884514 IC50 = 49330.0 nM 4.31
CHEMBL3884946 IC50 = 52540.0 nM 4.28
CHEMBL3883629 IC50 = 55280.0 nM 4.26
CHEMBL3885249 IC50 = 56610.0 nM 4.25
CHEMBL3885058 IC50 = 65550.0 nM 4.18
CHEMBL3885095 IC50 = 68230.0 nM 4.17
CHEMBL3885375 IC50 = 69030.0 nM 4.16
CHEMBL3885089 IC50 = 72270.0 nM 4.14
CHEMBL3884675 IC50 = 77440.0 nM 4.11
CHEMBL3883584 IC50 = 114870.0 nM -