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Assay Detail

CHEMBL3876376

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [125I]peptide YY from Y2 receptor in human KAN-TS cells measured after 60 mins by scintillation counting method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type KAN-TS
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Neuropeptide Y receptor type 2 (CHEMBL4018)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH3 or 2-CH3.
Gunia-Krzyżak A, Żelaszczyk D, Rapacz A, Żesławska E, Waszkielewicz AM, Pańczyk K, Słoczyńska K, Pękala E, Nitek W, Filipek B, Marona H.
Bioorg Med Chem (2017) 25 : 471 -482
PubMed 27876250 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 10.55 10.55

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL438945 HUMAN NEUROPEPTIDE Y 1.0 1 10.55

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL438945 HUMAN NEUROPEPTIDE Y IC50 = 0.028 nM 10.55